QuickView for TOP3 (gene)
- Gene Symbol:
- TOP3
Saccharomyces cerevisiae - Full name:
- DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination
- Synonyms:
- EDR1, TOP3, TOP3, YLR234W
- Genomic Location:
- Chr XII: 609785-611755
- Orthologs:
- Schizosaccharomyces pombe
- External Links:
- Entrez Gene
GO Molecular Function
isomerase activity | nucleic acid binding | catalytic activity | DNA binding | organic cyclic compound binding | DNA topoisomerase type I activity | heterocyclic compound binding | DNA topoisomerase activity
GO Biological Process
telomere maintenance | cellular process | telomere maintenance via telomerase | anatomical structure homeostasis | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | regulation of DNA recombination | chromosome segregation | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | telomere organization | cellular biosynthetic process | DNA recombination | telomere maintenance via telomere lengthening | nitrogen compound metabolic process | reproductive process | sister chromatid segregation | DNA biosynthetic process | mitotic sister chromatid cohesion | cell cycle | RNA-dependent DNA biosynthetic process | regulation of nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | nuclear chromosome segregation | DNA topological change | regulation of cellular metabolic process | homeostatic process | DNA metabolic process | reciprocal meiotic recombination | mitotic cell cycle | nuclear division | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | mitotic nuclear division | meiosis I | meiotic cell cycle | cellular macromolecule biosynthetic process | homologous recombination | organelle organization | sister chromatid cohesion | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | mitotic sister chromatid segregation | macromolecule metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | intracellular organelle | protein-containing complex | RecQ helicase-Topo III complex | membrane-bounded organelle | nucleus | organelle | intracellular
