QuickView for TPIP (gene)
- Gene Symbol:
- TPTE2
Homo sapiens - Full name:
- transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
- Synonyms:
- TPIP, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2, PTEN-like inositol lipid phosphatase, TPIP lipid phosphatase, TPTE and PTEN homologous inositol lipid phosphatase, lipid phosphatase TPIP, transmembrane phosphoinositide 3-phosphatase and tensin 2-like protein
- Genomic Location:
- Chr 13: 18895017-19008903
- Description:
-
TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
13q12.11
GO Molecular Function
phosphatidylinositol bisphosphate phosphatase activity | phosphatase activity | protein tyrosine/serine/threonine phosphatase activity | phosphatidylinositol trisphosphate phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | phosphatidylinositol phosphate phosphatase activity | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | phosphoric ester hydrolase activity
GO Biological Process
phosphatidylinositol bisphosphate phosphatase activity | protein dephosphorylation | phosphatidylinositol metabolic process | phospholipid metabolic process | cellular process | cellular lipid metabolic process | phosphatase activity | protein tyrosine/serine/threonine phosphatase activity | phosphatidylinositol trisphosphate phosphatase activity | protein modification process | cellular biosynthetic process | macromolecule modification | protein tyrosine phosphatase activity | nitrogen compound metabolic process | phosphorus metabolic process | lipid metabolic process | organophosphate metabolic process | phospholipid biosynthetic process | phosphoprotein phosphatase activity | biosynthetic process | lipid biosynthetic process | phosphatidylinositol phosphate phosphatase activity | phosphate-containing compound metabolic process | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | glycerolipid metabolic process | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | protein metabolic process | glycerophospholipid biosynthetic process | metabolic process | organic substance metabolic process | phosphatidylinositol biosynthetic process | dephosphorylation | cellular protein metabolic process | glycerophospholipid metabolic process | cellular protein modification process | peptidyl-tyrosine dephosphorylation | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | Golgi membrane | membrane-bounded organelle | organelle | intracellular | membrane
