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QuickView for TRIB1 (gene)


Gene Symbol:
TRIB1 Homo sapiens Homo sapiens
Full name:
tribbles pseudokinase 1
Synonyms:
C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1, tribbles homolog 1, G-protein-coupled receptor induced protein, G-protein-coupled receptor-induced gene 2 protein, G-protein-coupled receptor-induced protein 2, phosphoprotein regulated by mitogenic pathways, tribbles-like protein 1
Genomic Location:
Chr 8: 126511745-126519827
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
CGTSACG_PAX3_B GATTGGY_NFY_Q6_01 RTAAACA_FREAC2_01 FXR_Q3 HNF3ALPHA_Q6 TFIIA_Q6 TGANTCA_AP1_C CEBPA_01 USF_Q6 CREB_Q4_01
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8q24.13


Transcripts Names
NM_025195
XR_428373
NM_001282985
Protein Names
Q96RU8
C5HU08
O15180
Q9H2Y8



GO Molecular Function

kinase binding | protein kinase regulator activity | kinase regulator activity | protein kinase inhibitor activity | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | molecular function regulator | catalytic activity | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | mitogen-activated protein kinase kinase binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transcription factor binding | kinase inhibitor activity | ubiquitin protein ligase binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | ubiquitin-protein transferase regulator activity | heterocyclic compound binding | small molecule binding

GO Biological Process

negative regulation of phosphorylation | negative regulation of immune system process | response to lipopolysaccharide | intracellular signal transduction | regulation of cell development | regulation of localization | protein kinase regulator activity | regulation of immune system process | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | regulation of MAP kinase activity | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | negative regulation of neutrophil differentiation | positive regulation of protein catabolic process | negative regulation of protein phosphorylation | positive regulation of granulocyte differentiation | cellular process | regulation of cell motility | negative regulation of smooth muscle cell migration | negative regulation of signaling | kinase regulator activity | protein kinase inhibitor activity | regulation of proteolysis | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of cellular metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | negative regulation of cell motility | regulation of cellular process | regulation of metabolic process | negative regulation of granulocyte differentiation | positive regulation of cellular protein metabolic process | MAPK cascade | positive regulation of cellular protein catabolic process | response to stimulus | enzyme inhibitor activity | JNK cascade | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of cellular protein catabolic process | response to stress | negative regulation of protein kinase activity | regulation of cell proliferation | regulation of granulocyte differentiation | regulation of smooth muscle cell migration | positive regulation of proteolysis involved in cellular protein catabolic process | positive regulation of proteolysis | response to molecule of bacterial origin | negative regulation of metabolic process | negative regulation of hemopoiesis | protein modification process | macromolecule modification | molecular function regulator | stress-activated protein kinase signaling cascade | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | regulation of neutrophil differentiation | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | negative regulation of smooth muscle cell proliferation | negative regulation of myeloid cell differentiation | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of DNA-binding transcription factor activity | regulation of cellular component movement | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | stress-activated MAPK cascade | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein metabolic process | response to organic substance | regulation of hemopoiesis | kinase inhibitor activity | regulation of kinase activity | regulation of lipopolysaccharide-mediated signaling pathway | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | metabolic process | positive regulation of cell development | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | regulation of proteasomal protein catabolic process | protein kinase activity | organic substance metabolic process | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | regulation of phosphate metabolic process | negative regulation of protein metabolic process | regulation of cell communication | regulation of macrophage differentiation | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | enzyme regulator activity | response to biotic stimulus | regulation of developmental process | kinase activity | ubiquitin-protein transferase regulator activity | cellular protein modification process | negative regulation of cell proliferation | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | cellular metabolic process | negative regulation of lipopolysaccharide-mediated signaling pathway | regulation of smooth muscle cell proliferation | positive regulation of eosinophil differentiation | regulation of ubiquitin-dependent protein catabolic process | negative regulation of locomotion | negative regulation of myeloid leukocyte differentiation | negative regulation of cell differentiation | response to other organism | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular