QuickView for TRID (gene)
- Gene Symbol:
- TNFRSF10C
Homo sapiens - Full name:
- TNF receptor superfamily member 10c
- Synonyms:
- CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, tumor necrosis factor receptor superfamily member 10C, TNF-related apoptosis-inducing ligand receptor 3, antagonist decoy receptor for TRAIL/Apo-2L, cytotoxic TRAIL receptor-3, decoy TRAIL receptor without death domain, decoy receptor 1, lymphocyte inhibitor of TRAIL, tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
- Genomic Location:
- Chr 8: 23016379-23030895
- Description:
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apop...
- Orthologs:
- Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
8p21.3
GO Molecular Function
TRAIL binding | transmembrane signaling receptor activity | signaling receptor activity | protein binding
GO Biological Process
response to cytokine | regulation of programmed cell death | cellular response to tumor necrosis factor | cellular process | regulation of cellular process | regulation of apoptotic process | response to stimulus | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cell communication | response to organic substance | cell surface receptor signaling pathway | tumor necrosis factor-mediated signaling pathway | signaling | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | signal transduction
GO Cellular Component
cell | intrinsic component of membrane | plasma membrane | anchored component of membrane | cell periphery | membrane
