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QuickView for TRIM13 (gene)


Gene Symbol:
TRIM13 Homo sapiens Homo sapiens
Full name:
tripartite motif containing 13
Synonyms:
CAR, DLEU5, LEU5, RFP2, RNF77, E3 ubiquitin-protein ligase TRIM13, B-cell chronic lymphocytic leukemia tumor suppressor Leu5, CLL-associated RING finger, RING finger protein 77, RING-type E3 ubiquitin transferase TRIM13, leukemia-associated protein 5, putative tumor suppressor RFP2, ret finger protein 2, tripartite motif protein 13, tripartite motif-containing protein 13
Genomic Location:
Chr 13: 49469144-49490604
Description:
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variant...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 13
13q14.2





GO Molecular Function

cation binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | protein binding | zinc ion binding | ubiquitin-protein transferase activity | transferase activity | transition metal ion binding | ubiquitin-like protein ligase activity | metal ion binding

GO Biological Process

response to radiation | response to endoplasmic reticulum stress | proteolysis | positive regulation of DNA-binding transcription factor activity | negative regulation of viral release from host cell | regulation of autophagy | defense response | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | endoplasmic reticulum mannose trimming | negative regulation of viral life cycle | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of viral release from host cell | response to stimulus | response to stress | protein deglycosylation | cellular protein catabolic process | proteasomal protein catabolic process | regulation of macroautophagy | protein modification process | macromolecule modification | regulation of nucleic acid-templated transcription | response to nitrogen compound | nitrogen compound metabolic process | regulation of signal transduction | regulation of gene expression | cellular response to stress | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of intracellular signal transduction | ubiquitin protein ligase activity | negative regulation of viral process | response to gamma radiation | regulation of cellular metabolic process | positive regulation of signal transduction | regulation of locomotion | regulation of RNA metabolic process | regulation of viral process | proteasome-mediated ubiquitin-dependent protein catabolic process | positive regulation of molecular function | ERAD pathway | protein metabolic process | response to organic substance | protein ubiquitination | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | cellular macromolecule catabolic process | protein autoubiquitination | anatomical structure development | metabolic process | ubiquitin-protein transferase activity | regulation of RNA biosynthetic process | positive regulation of cell death | immune response | organic substance metabolic process | positive regulation of NF-kappaB transcription factor activity | protein modification by small protein conjugation or removal | positive regulation of autophagy | positive regulation of macroautophagy | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | anatomical structure morphogenesis | developmental process | cellular protein modification process | carbohydrate derivative metabolic process | innate immune response | response to organonitrogen compound | ubiquitin-dependent ERAD pathway | regulation of viral transcription | positive regulation of metabolic process | immune system process | cellular metabolic process | regulation of cell death | modification-dependent protein catabolic process | regulation of viral life cycle | glycoprotein metabolic process | negative regulation of locomotion | protein alpha-1,2-demannosylation | negative regulation of viral transcription | regulation of I-kappaB kinase/NF-kappaB signaling | response to ionizing radiation | positive regulation of signaling | regulation of signaling | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | perinuclear region of cytoplasm | membrane-bounded organelle | organelle | perinuclear endoplasmic reticulum | intracellular | endoplasmic reticulum quality control compartment | membrane