QuickView for TRIM37;jsessionid=99CEFBF63055010B1028CCEE213BDA9A (gene)

Gene Symbol:

TRIM37 Homo sapiens

Full name:

tripartite motif containing 37

Synonyms:

MUL, POB1, TEF3, E3 ubiquitin-protein ligase TRIM37, RING-B-box-coiled-coil protein, RING-type E3 ubiquitin transferase TRIM37, mulibrey nanism protein

Genomic Location:

Chr 17: 54414792-54539011

Description:

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved ...

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This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CMYB_01 ,  CEBPA_01 ,  MYOD_01 ,  TAL1ALPHAE47_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  TAL1BETAE47_01 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  TGTTTGY_HNF3_Q6 ,  USF_01 ,  TAL1BETAITF2_01 ,  RCGCANGCGY_NRF1_Q6 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-29

Cytogenetic Map:

17q22

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