QuickView for TRPC6 (gene)

Gene Symbol:

TRPC6 Homo sapiens

Full name:

transient receptor potential cation channel subfamily C member 6

Synonyms:

FSGS2, TRP6, short transient receptor potential channel 6, TRP-6, focal segmental glomerulosclerosis 2, transient receptor protein 6

Genomic Location:

Chr 11: 100827584-100959869

Description:

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular...

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The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  YATTNATC_UNKNOWN ,  RGAANNTTC_HSF1_01

Cytogenetic Map:

11q22.1

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