QuickView for TRUNDD (gene)
- Gene Symbol:
- TNFRSF10D
Homo sapiens - Full name:
- TNF receptor superfamily member 10d
- Synonyms:
- CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, tumor necrosis factor receptor superfamily member 10D, TNF receptor-related receptor for TRAIL, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL receptor with a truncated death domain, decoy receptor 2, tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
- Genomic Location:
- Chr 8: 23049046-23077485
- Description:
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.
- Orthologs:
- Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
8p21.3
GO Molecular Function
TRAIL binding | transmembrane signaling receptor activity | signaling receptor activity | protein binding
GO Biological Process
response to cytokine | cell motility | regulation of programmed cell death | negative regulation of cellular process | cellular response to tumor necrosis factor | cellular process | localization | negative regulation of apoptotic process | regulation of cellular process | regulation of apoptotic process | response to stimulus | leukocyte migration | locomotion | cell migration | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cell communication | response to organic substance | cell surface receptor signaling pathway | negative regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | signaling | immune system process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | negative regulation of cell death | signal transduction
