QuickView for TSPAN-2 (gene)

Gene Symbol:

TSPAN2 Homo sapiens

Full name:

tetraspanin 2

Synonyms:

NET3, TSN2, TSPAN-2, tetraspanin-2, new EST tetraspan 3, tetraspan 2, tetraspan NET-3, tetraspan TM4SF, tetraspanin 2 isoform

Genomic Location:

Chr 1: 115392155-115433638

Description:

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,...

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  POU6F1_01 ,  TTANTCA_UNKNOWN ,  GTAAACC_MIR2995P ,  CTTTGA_LEF1_Q2 ,  TCF4_Q5 ,  GGGAGGRR_MAZ_Q6 ,  TFIII_Q6 ,  SOX9_B1 ,  LEF1_Q2 ,  CAGGTG_E12_Q6 ,  ATACCTC_MIR202 ,  NKX25_02 ,  CTCTGGA_MIR520A_MIR525 ,  PAX8_B ,  AREB6_03 ,  AP2_Q6 ,  TTGTTT_FOXO4_01 ,  SNACANNNYSYAGA_UNKNOWN ,  ICSBP_Q6 ,  RNTCANNRNNYNATTW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  AAACCAC_MIR140 ,  AACTTT_UNKNOWN ,  NFKB_Q6 ,  SRF_C ,  ETF_Q6 ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-140

Cytogenetic Map:

1p13.2

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