QuickView for TTPA (gene)

Gene Symbol:

TTPA Homo sapiens

Full name:

alpha tocopherol transfer protein

Synonyms:

ATTP, AVED, TTP1, alphaTTP, alpha-tocopherol transfer protein, alpha-TTP, tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)

Genomic Location:

Chr 8: 64135985-64161166

Description:

This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutat...

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This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

8q12.3

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