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QuickView for TTPA (gene)

Gene Symbol:
TTPA Homo sapiens Homo sapiens
Full name:
alpha tocopherol transfer protein
ATTP, AVED, TTP1, alphaTTP, alpha-tocopherol transfer protein, alpha-TTP, tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
Genomic Location:
Chr 8: 64135985-64161166
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutat...
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Cytogenetic Map:
chr 8

Transcripts Names
Protein Names

GO Molecular Function

phosphatidylinositol-4,5-bisphosphate binding | lipid binding | vitamin binding | phospholipid binding | phosphatidylinositol-3,4-bisphosphate binding | anion binding | phosphatidylinositol bisphosphate binding | transporter activity | ion binding | organic cyclic compound binding | protein binding | intermembrane lipid transfer activity | phosphatidylinositol binding | lipid transporter activity | heterocyclic compound binding | small molecule binding | phosphatidylinositol phosphate binding | vitamin E binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | developmental process involved in reproduction | regulation of cell development | lipid transport | establishment of localization | negative regulation of cellular process | cellular chemical homeostasis | membrane organization | cellular process | localization | cellular homeostasis | regulation of establishment of blood-brain barrier | reproductive system development | macromolecule localization | regulation of cell differentiation | regulation of cellular process | organic cyclic compound metabolic process | cellular component organization | pH reduction | response to stimulus | intracellular pH reduction | reproduction | embryo development | response to pH | embryonic placenta development | organic hydroxy compound metabolic process | system development | reproductive process | multicellular organism development | vitamin transport | lipid metabolic process | organic substance transport | cellular ion homeostasis | small molecule metabolic process | response to nutrient | response to toxic substance | cation homeostasis | chordate embryonic development | cellular cation homeostasis | regulation of intracellular pH | homeostatic process | embryo development ending in birth or egg hatching | intermembrane lipid transfer activity | vitamin metabolic process | regulation of pH | anatomical structure development | vitamin E metabolic process | metabolic process | lipid localization | embryonic organ development | chemical homeostasis | intermembrane lipid transfer | organic substance metabolic process | animal organ development | ion homeostasis | regulation of cellular pH | cellular monovalent inorganic cation homeostasis | reproductive structure development | regulation of developmental process | developmental process | negative regulation of establishment of blood-brain barrier | heterocycle metabolic process | in utero embryonic development | lipid transporter activity | cellular metabolic process | placenta development | regulation of cell death | negative regulation of cell death | negative regulation of cell development | negative regulation of cell differentiation | multicellular organismal process

GO Cellular Component

late endosome | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | endomembrane system | vesicle | endosome | membrane-bounded organelle | organelle | cytosol | intracellular vesicle | intracellular