QuickView for TUBA4A (gene)

Gene Symbol:

TUBA4A Homo sapiens

Full name:

tubulin alpha 4a

Synonyms:

ALS22, H2-ALPHA, TUBA1, tubulin alpha-4A chain, tubulin H2-alpha, tubulin alpha-1 chain, tubulin, alpha 1 (testis specific)

Genomic Location:

Chr 2: 219823245-219826882

Description:

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all euk...

View Full Description

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYOD_Q6_01 ,  AP1_C ,  TGANTCA_AP1_C ,  MYOD_01 ,  AREB6_02 ,  TGANNYRGCA_TCF11MAFG_01 ,  CACGTG_MYC_Q2 ,  MAX_01 ,  AMEF2_Q6 ,  AP1_Q6 ,  ARNT_02 ,  E2A_Q2 ,  CTAWWWATA_RSRFC4_Q2 ,  HEB_Q6 ,  TATAAA_TATA_01 ,  CDPCR3HD_01 ,  NFE2_01 ,  AP1_Q6_01 ,  LFA1_Q6 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  MYCMAX_01 ,  CDPCR1_01 ,  AREB6_01 ,  NRF2_Q4 ,  AP4_Q6_01 ,  ARGGGTTAA_UNKNOWN ,  TATA_01 ,  CTGCAGY_UNKNOWN ,  TBP_01 ,  CAGCTG_AP4_Q5 ,  KTGGYRSGAA_UNKNOWN ,  MMEF2_Q6 ,  GGGTGGRR_PAX4_03 ,  TGASTMAGC_NFE2_01

View More

View Less

Cytogenetic Map:

2q35

search → result