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QuickView for TUC4 (gene)


Gene Symbol:
Dpysl3 Mus musculus Mus musculus
Full name:
dihydropyrimidinase-like 3
Synonyms:
CRMP-4, DRP-3, TUC4, ULIP-1, Ulip, Ulip1, dihydropyrimidinase-related protein 3, collapsin response mediator protein 4, unc-33-like phosphoprotein 1
Genomic Location:
Chr 18: 43483936-43552985
Description:
This gene encodes a protein that belongs to the TUC (TOAD-64/Ulip/CRMP) family of proteins. Members of this family are phosphoproteins that function in axonal guidance and neuronal differentiation during development and regeneration of the nervous system. A mutation in the human gene is associated with amyotrophic lateral sclerosis. Alternative spl...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_009468
NM_001136086
NM_001291455
Protein Names
Q3TT92
E9PWE8
Q62188



GO Molecular Function

filamin binding | SH3 domain binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | protein domain specific binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | cytoskeletal protein binding | anion binding | chondroitin sulfate binding | ion binding | phosphoprotein binding | protein binding | glycosaminoglycan binding

GO Biological Process

protein homooligomerization | actin filament-based process | positive regulation of cellular component organization | positive regulation of filopodium assembly | regulation of neurogenesis | regulation of cell development | regulation of localization | actin filament bundle organization | actin cytoskeleton organization | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | neurogenesis | generation of neurons | cellular process | regulation of cell motility | negative regulation of cell migration | regulation of neuron projection development | regulation of cell differentiation | actin crosslink formation | negative regulation of cell motility | regulation of cellular process | cellular component organization | response to stimulus | response to stress | negative regulation of neuron projection development | supramolecular fiber organization | cellular component assembly | regulation of cell projection assembly | system development | positive regulation of neuron projection development | multicellular organism development | actin filament organization | protein complex oligomerization | regulation of neuron differentiation | response to axon injury | regulation of cell migration | positive regulation of cell projection organization | regulation of cellular component movement | actin filament bundle assembly | positive regulation of cell differentiation | regulation of locomotion | regulation of filopodium assembly | protein-containing complex assembly | negative regulation of cell projection organization | response to wounding | anatomical structure development | positive regulation of neurogenesis | positive regulation of cell development | positive regulation of cellular component biogenesis | negative regulation of neuron differentiation | negative regulation of cellular component movement | cytoskeleton organization | positive regulation of plasma membrane bounded cell projection assembly | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | positive regulation of neuron differentiation | regulation of cell projection organization | negative regulation of cell development | negative regulation of locomotion | negative regulation of cell differentiation | regulation of cellular component organization | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

supramolecular fiber | exocytic vesicle | neuron projection | cytoplasmic vesicle | cell body | cell | distal axon | lamellipodium | cytoplasm | intracellular organelle | actin cytoskeleton | protein-containing complex | cell projection | secretory vesicle | endomembrane system | cell leading edge | vesicle | transport vesicle | filamentous actin | site of polarized growth | extracellular region | membrane-bounded organelle | organelle | extracellular space | axon | growth cone | cytosol | intracellular vesicle | actin filament | cytoskeleton | intracellular | supramolecular complex