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QuickView for TUT1 (gene)


Gene Symbol:
TUT1 Homo sapiens Homo sapiens
Full name:
terminal uridylyl transferase 1, U6 snRNA-specific
Synonyms:
PAPD2, RBM21, STARPAP, TUTase, URLC6, speckle targeted PIP5K1A-regulated poly(A) polymerase, PAP-associated domain-containing 2, RNA uridylyltransferase, RNA-binding motif protein 21, RNA-binding protein 21, TUTase 6, U6 snRNA-specific terminal uridylyltransferase 1, U6-TUTase, nuclear speckle targeted phosphatidylinositol 4-phosphate 5-kinase type I-alpha regulated-poly(A) polymerase, nuclear speckle-targeted PIPK1A-regulated-poly(A) polymerase, poly(A) polymerase associated domain containing 2, star-PAP, up-regulated in lung cancer 6
Genomic Location:
Chr 11: 62099096-62115592
Description:
This gene encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q12.3


Transcripts Names
NM_022830



GO Molecular Function

cation binding | enzyme binding | nucleic acid binding | ribonucleotide binding | mRNA binding | nucleotide binding | carbohydrate derivative binding | nucleotidyltransferase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | RNA uridylyltransferase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | adenylyltransferase activity | transferase activity | polynucleotide adenylyltransferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | mRNA 3'-UTR binding | metal ion binding | heterocyclic compound binding | uridylyltransferase activity | small molecule binding | RNA binding

GO Biological Process

RNA metabolic process | snRNA metabolic process | RNA processing | mRNA cleavage | cellular process | organic substance catabolic process | histone mRNA catabolic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | histone mRNA metabolic process | ncRNA processing | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | mRNA polyadenylation | RNA polyadenylation | nitrogen compound metabolic process | regulation of gene expression | RNA catabolic process | snRNA processing | aromatic compound catabolic process | cellular macromolecule catabolic process | metabolic process | RNA 3'-end processing | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | RNA phosphodiester bond hydrolysis | gene expression | ncRNA metabolic process | heterocycle metabolic process | mRNA 3'-end processing | cellular metabolic process | pre-mRNA cleavage required for polyadenylation | mRNA processing | mRNA cleavage involved in mRNA processing | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | mRNA cleavage factor complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | mRNA cleavage and polyadenylation specificity factor complex | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular