QuickView for TUWD12 (gene)

Gene Symbol:

POC1B Homo sapiens

Full name:

POC1 centriolar protein B

Synonyms:

CORD20, PIX1, TUWD12, WDR51B, POC1 centriolar protein homolog B, WD repeat-containing protein 51B, proteome of centriole protein 1B

Genomic Location:

Chr 12: 88337632-88443908

Description:

POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multip...

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POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Rattus norvegicus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

WGTTNNNNNAAA_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  CDPCR3HD_01 ,  MYCMAX_02 ,  RGAGGAARY_PU1_Q6 ,  YWATTWNNRGCT_UNKNOWN ,  AACTTT_UNKNOWN ,  PAX2_02

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-217

Cytogenetic Map:

12q21.33

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