QuickView for Tcerg1 (gene)
- Gene Symbol:
- TCERG1
Homo sapiens - Full name:
- transcription elongation regulator 1
- Synonyms:
- CA150, TAF2S, Urn1, transcription elongation regulator 1, TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD, TATA box-binding protein-associated factor 2S, co-activator of 150 kDa, transcription factor CA150
- Genomic Location:
- Chr 5: 145807066-145871262
- Description:
-
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encod...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-223 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-299 , Predicted Gene Targets for miR-330 , Predicted Gene Targets for miR-369-3p , Predicted Gene Targets for miR-7 , Predicted Gene Targets for miR-374
- Cytogenetic Map:
-
5q32
GO Molecular Function
RNA polymerase binding | repressing transcription factor binding | enzyme binding | nucleic acid binding | proline-rich region binding | RNA polymerase II repressing transcription factor binding | transcription corepressor activity | identical protein binding | organic cyclic compound binding | transcription coactivator activity | protein binding | transcription factor binding | RNA polymerase II transcription factor binding | transcription coregulator activity | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | negative regulation of transcription by RNA polymerase II | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
