QuickView for Tcfpu1 (gene)
- Gene Symbol:
- Spi1
Mus musculus - Full name:
- spleen focus forming virus (SFFV) proviral integration oncogene
- Synonyms:
- Dis-1, Dis1, PU.1, Sfpi-1, Sfpi1, Spi-1, Tcfpu1, Tfpu.1, transcription factor PU.1, 31 kDa-transforming protein, SFFV proviral integration 1 protein, hematopoietic transcription factor PU.1
- Genomic Location:
- Chr 2: 90936954-90955913
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- miRNA binding sites
(Source: miRecords):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | enhancer binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | NFAT protein binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | somatic stem cell population maintenance | peptidyl-amino acid modification | erythrocyte homeostasis | regulation of DNA methylation | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | pri-miRNA transcription by RNA polymerase II | negative regulation of RNA biosynthetic process | histone modification | cell differentiation | histone H3 acetylation | regulation of organelle organization | anatomical structure regression | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | regulation of gene expression, epigenetic | lymphocyte differentiation | chromatin organization | lymphoid progenitor cell differentiation | immune system development | negative regulation of nucleic acid-templated transcription | stem cell population maintenance | regulation of histone modification | myeloid dendritic cell differentiation | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of peptidyl-lysine acetylation | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | leukocyte activation | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | vasculature development | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | cellular nitrogen compound biosynthetic process | tube morphogenesis | hematopoietic progenitor cell differentiation | programmed cell death | cardiovascular system development | peptidyl-lysine acetylation | macrophage differentiation | cellular nitrogen compound metabolic process | myeloid dendritic cell activation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | cellular biosynthetic process | macromolecule modification | negative regulation of histone H4 acetylation | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | leukocyte differentiation | apoptotic process | negative regulation of MHC class II biosynthetic process | system development | nitrogen compound metabolic process | multicellular organism development | protein acetylation | regulation of gene expression | regulation of histone H4 acetylation | myeloid leukocyte differentiation | negative regulation of gene expression, epigenetic | positive regulation of cellular metabolic process | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | homeostasis of number of cells | granulocyte differentiation | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of pri-miRNA transcription by RNA polymerase II | hypermethylation of CpG island | regulation of cellular metabolic process | regulation of protein metabolic process | apoptotic process involved in development | homeostatic process | regulation of RNA metabolic process | lymphocyte activation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein metabolic process | DNA-binding transcription factor activity | regulation of hemopoiesis | DNA hypermethylation | anatomical structure development | metabolic process | dendritic cell differentiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of histone acetylation | regulation of erythrocyte differentiation | peptidyl-lysine modification | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of chromosome organization | transcription, DNA-templated | cell activation | negative regulation of protein metabolic process | negative regulation of chromosome organization | covalent chromatin modification | regulation of transcription, DNA-templated | internal protein amino acid acetylation | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | organelle organization | erythrocyte differentiation | cellular protein modification process | regulation of histone acetylation | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | negative regulation of protein acetylation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | apoptotic process involved in morphogenesis | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | circulatory system development | regulation of cellular component organization | apoptotic process involved in blood vessel morphogenesis | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
