QuickView for Testes-1 (gene)
- Gene Symbol:
- Pou3f1
Rattus norvegicus - Full name:
- POU class 3 homeobox 1
- Synonyms:
- Oct-6, Otf6, Scip, Testes-1, Tst-1, POU domain, class 3, transcription factor 1, OTF-6, POU domain transcription factor SCIP, octamer-binding protein 6, octamer-binding transcription factor 6, octoamer transcription factor-6, octomer-6, suppressed cAMP-inducible POU
- Genomic Location:
- Chr 5: 143981547-143984527
- Description:
-
may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , NMYC_01 , GATA1_01 , GATA2_01 , NGFIC_01 , GFI1_01 , AP2ALPHA_01 , AP2GAMMA_01 , CDC5_01 , ZF5_01
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transcription coregulator activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | brain development | positive regulation of macromolecule biosynthetic process | Schwann cell differentiation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | neurogenesis | positive regulation of cellular biosynthetic process | cellular process | peripheral nervous system development | axon ensheathment | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | gliogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | head development | cellular nitrogen compound biosynthetic process | ensheathment of neurons | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | myelination | multicellular organism development | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | epidermal cell differentiation | biosynthetic process | aromatic compound biosynthetic process | glial cell differentiation | epidermis development | skin development | keratinocyte differentiation | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | DNA-binding transcription factor activity | anatomical structure development | Schwann cell development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transcription, DNA-templated | regulation of transcription, DNA-templated | glial cell development | cell development | cellular macromolecule biosynthetic process | developmental process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | cellular metabolic process | myelination in peripheral nervous system | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
