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QuickView for Tf2a (gene)


Gene Symbol:
Gtf2a1 Rattus norvegicus Rattus norvegicus
Full name:
general transcription factor 2A subunit 1
Synonyms:
Tf2a, TfIIa, transcription initiation factor IIA subunit 1, TFIIA large subunit, general transcription factor 2a, 1, general transcription factor IIA subunit 1, general transcription factor IIa, 1 (37kD and 19kD subunits)
Genomic Location:
Chr 6: 115180871-115210825
Description:
large subunit of transcription factor 2a; human homolog interacts with the TATA-binding protein to act early during preinitiation complex formation
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
ATF_01 COMP1_01 YY1_01 YY1_02 CREB_02 TAXCREB_01 USF_01 USF_02 HFH1_01 HNF3B_01
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_022208
XM_006240410
Protein Names
O08949



GO Molecular Function

repressing transcription factor binding | nucleic acid binding | RNA polymerase II repressing transcription factor binding | DNA binding | protein heterodimerization activity | organic cyclic compound binding | protein binding | transcription factor binding | TBP-class protein binding | RNA polymerase II transcription factor binding | protein dimerization activity | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | transcription factor TFIIA complex | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | cytosol | intracellular | RNA polymerase II, holoenzyme