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QuickView for Timp4 (gene)


Gene Symbol:
TIMP4 Homo sapiens Homo sapiens
Full name:
TIMP metallopeptidase inhibitor 4
Synonyms:
TIMP-4, metalloproteinase inhibitor 4, tissue inhibitor of metalloproteinase 4, tissue inhibitor of metalloproteinases 4
Genomic Location:
Chr 3: 12169568-12175647
Description:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may ...
Orthologs:
Mus musculus Rattus norvegicus Danio rerio Bos taurus Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p25.2


Transcripts Names
NM_003256
Protein Names
B2R7K6
Q99727



GO Molecular Function

endopeptidase inhibitor activity | cation binding | enzyme binding | enzyme inhibitor activity | molecular function regulator | ion binding | protein binding | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | protease binding | metal ion binding

GO Biological Process

Notch signaling pathway | negative regulation of membrane protein ectodomain proteolysis | endopeptidase inhibitor activity | response to cytokine | response to lipopolysaccharide | response to hormone | negative regulation of cellular process | nervous system development | response to drug | negative regulation of proteolysis | cellular process | multicellular organismal reproductive process | regulation of proteolysis | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cellular process | regulation of metabolic process | response to stimulus | enzyme inhibitor activity | ovulation cycle | response to peptide | reproduction | rhythmic process | response to molecule of bacterial origin | negative regulation of metabolic process | molecular function regulator | response to nitrogen compound | response to external biotic stimulus | system development | reproductive process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | response to lipid | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | multicellular organism reproduction | response to organic substance | anatomical structure development | cell surface receptor signaling pathway | regulation of protein catabolic process | negative regulation of cellular protein metabolic process | negative regulation of protein catabolic process | negative regulation of protein metabolic process | negative regulation of molecular function | signaling | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | response to biotic stimulus | developmental process | response to organonitrogen compound | negative regulation of hydrolase activity | central nervous system development | response to other organism | signal transduction | negative regulation of endopeptidase activity | multicellular organismal process

GO Cellular Component

supramolecular fiber | extracellular matrix | sarcomere | cell | myofibril | cytoplasm | intracellular organelle | contractile fiber | extracellular region | organelle | extracellular space | intracellular | supramolecular complex