QuickView for Tmod2 (gene)

Gene Symbol:

TMOD2 Homo sapiens

Full name:

tropomodulin 2

Synonyms:

N-TMOD, NTMOD, tropomodulin-2, neuronal tropomodulin, tropomodulin 2 (neuronal)

Genomic Location:

Chr 15: 49831102-49889635

Description:

This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding d...

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This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  HNF4ALPHA_Q6 ,  OCT1_05 ,  OCT1_B ,  OCT_Q6 ,  ZF5_01 ,  TTCCGTT_MIR191 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  OCT1_Q5_01 ,  OCT_C ,  OCT1_Q6 ,  ACATTCC_MIR1_MIR206 ,  CTTTGT_LEF1_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-191 ,  Predicted Gene Targets for miR-30

Cytogenetic Map:

15q21.2

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