QuickView for Tox3 (gene)
- Gene Symbol:
- TOX3
Homo sapiens - Full name:
- TOX high mobility group box family member 3
- Synonyms:
- CAGF9, TNRC9, TOX high mobility group box family member 3, CAG trinucleotide repeat-containing gene F9 protein, trinucleotide repeat-containing gene 9 protein
- Genomic Location:
- Chr 16: 51029418-51138307
- Description:
-
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two t...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
16q12.1
| Transcripts Names |
|---|
| NM_001080430 |
| XM_931515 |
| XM_049037 |
| XM_941030 |
| XM_944953 |
| NM_001146188 |
| XM_017023142 |
| XM_011523002 |
| XM_024450230 |
| XM_005255892 |
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | phosphoprotein binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein dimerization activity | estrogen response element binding | RNA polymerase II regulatory region sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | regulation of programmed cell death | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | programmed cell death | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | negative regulation of neuron apoptotic process | apoptotic process | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
