QuickView for Tpi1 (gene)

Gene Symbol:

TPI1 Homo sapiens

Full name:

triosephosphate isomerase 1

Synonyms:

HEL-S-49, TIM, TPI, TPID, triosephosphate isomerase, epididymis secretory protein Li 49, triose-phosphate isomerase

Genomic Location:

Chr 12: 6846967-6850253

Description:

This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 a...

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This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TTANTCA_UNKNOWN ,  GGGACCA_MIR133A_MIR133B ,  TGACCTY_ERR1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  HNF4_01 ,  CAGNYGKNAAA_UNKNOWN ,  E47_02 ,  GCM_Q2 ,  TGCCAAR_NF1_Q6 ,  TGTTTGY_HNF3_Q6 ,  YTAAYNGCT_UNKNOWN ,  CAGCTG_AP4_Q5

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133

miRNA binding sites
(Source: miRecords):

hsa-miR-15a/hsa-miR-16 Targeted Genes

Cytogenetic Map:

12p13.31

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