QuickView for Tpit (gene)

Gene Symbol:

TBX19 Homo sapiens

Full name:

T-box 19

Synonyms:

TBS19, TPIT, dJ747L4.1, T-box transcription factor TBX19, T-box factor, pituitary, T-box protein 19, TBS 19

Genomic Location:

Chr 1: 166516902-166550288

Description:

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role f...

View Full Description

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  TTANTCA_UNKNOWN ,  AREB6_02 ,  AP3_Q6 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  LHX3_01 ,  CCAWYNNGAAR_UNKNOWN ,  LMO2COM_02 ,  NKX25_02 ,  RAAGNYNNCTTY_UNKNOWN ,  GTGCCTT_MIR506 ,  TAATTA_CHX10_01 ,  IK2_01 ,  YTAATTAA_LHX3_01 ,  IK1_01 ,  TTANWNANTGGM_UNKNOWN

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a

Cytogenetic Map:

1q24.2

search → result