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QuickView for Tpl1 (gene)


Gene Symbol:
Ets1 Mus musculus Mus musculus
Full name:
E26 avian leukemia oncogene 1, 5' domain
Synonyms:
AI196000, AI448617, D230050P06, Ets-1, Tpl1, vs, protein C-ets-1, avian erythroblastosis virus E26 oncogene 1, p54, tumor progression locus 1
Genomic Location:
Chr 9: 32503627-32565405
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
IK2_01 CAGNYGKNAAA_UNKNOWN GFI1_01 MEIS1_01 NKX62_Q2 STAT4_01 STAT5A_04 GATA4_Q3 GR_Q6_01 PR_01
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-1 Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-125 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-139 Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-145 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-193 Predicted Gene Targets for miR-199





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | histone acetyltransferase binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of erythrocyte differentiation | nucleus organization | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of leukocyte adhesion to vascular endothelial cell | cell motility | regulation of localization | regulation of programmed cell death | regulation of immune system process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | pri-miRNA transcription by RNA polymerase II | cell differentiation | regulation of extracellular matrix organization | positive regulation of cell adhesion | positive regulation of cellular component movement | response to antibiotic | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | regulation of cell motility | localization | regulation of cell cycle | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | positive regulation of epithelial cell migration | regulation of vasculature development | response to stimulus | regulation of extracellular matrix disassembly | positive regulation of immune system process | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | positive regulation of cell-cell adhesion | cellular nitrogen compound metabolic process | positive regulation of blood vessel endothelial cell migration | positive regulation of RNA biosynthetic process | regulation of cell adhesion | cellular biosynthetic process | regulation of nucleic acid-templated transcription | locomotion | nitrogen compound metabolic process | positive regulation of inflammatory response | regulation of gene expression | positive regulation of cellular metabolic process | PML body organization | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | regulation of endothelial cell migration | positive regulation of myeloid cell differentiation | positive regulation of cell migration | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of locomotion | regulation of RNA metabolic process | DNA-binding transcription factor activity | regulation of hemopoiesis | metabolic process | regulation of RNA biosynthetic process | regulation of erythrocyte differentiation | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | nuclear body organization | transcription, DNA-templated | positive regulation of endothelial cell migration | negative regulation of cell cycle | regulation of epithelial cell migration | regulation of blood vessel endothelial cell migration | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | organelle organization | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | regulation of cell death | positive regulation of cell motility | regulation of inflammatory response | positive regulation of leukocyte cell-cell adhesion | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular