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QuickView for Tpst2 (gene)


Gene Symbol:
TPST2 Homo sapiens Homo sapiens
Full name:
tyrosylprotein sulfotransferase 2
Synonyms:
TANGO13B, protein-tyrosine sulfotransferase 2, TPST-2, transport and golgi organization 13 homolog B, tyrosylprotein phosphotransferase 2
Genomic Location:
Chr 22: 25251714-25316089
Description:
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 22
22q12.1





GO Molecular Function

catalytic activity | transferase activity, transferring sulfur-containing groups | sulfotransferase activity | protein-tyrosine sulfotransferase activity | identical protein binding | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity

GO Biological Process

purine ribonucleotide metabolic process | peptidyl-tyrosine sulfation | sulfur compound metabolic process | peptidyl-amino acid modification | cellular process | nucleotide metabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | protein sulfation | purine nucleotide metabolic process | cellular nitrogen compound metabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | phosphorus metabolic process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process | organophosphate metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | phosphate-containing compound metabolic process | protein metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organic acid metabolic process | cellular protein metabolic process | sulfation | cellular protein modification process | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | endomembrane system | Golgi membrane | membrane-bounded organelle | organelle | intracellular | membrane