QuickView for Tug1 (gene)

Gene Symbol:

TUG1 Homo sapiens

Full name:

taurine up-regulated 1 (non-protein coding)

Synonyms:

LINC00080, NCRNA00080, TI-227H, TUG1 noncoding RNA, long intergenic non-protein coding RNA 80, taurine upregulated gene 1

Genomic Location:

Chr 22: 29695634-29705381

Description:

This gene produces a long non-coding RNA that interacts with the Polycomb repressor complex and functions in the epigenetic regulation of transcription. This RNA promotes cell proliferation and is upregulated in tumor cells. It may act as a sponge for microRNAs. The homologous mouse gene is required for differentiation of retina. Alternative splici...

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This gene produces a long non-coding RNA that interacts with the Polycomb repressor complex and functions in the epigenetic regulation of transcription. This RNA promotes cell proliferation and is upregulated in tumor cells. It may act as a sponge for microRNAs. The homologous mouse gene is required for differentiation of retina. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Macaca mulatta

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  CMYB_01 ,  TCANNTGAY_SREBP1_01 ,  MZF1_01 ,  ZIC1_01 ,  CACGTG_MYC_Q2 ,  NKX3A_01 ,  GCANCTGNY_MYOD_Q6 ,  NGFIC_01 ,  HFH1_01 ,  ATF4_Q2 ,  STAT6_01 ,  ARNT_02 ,  IRF1_Q6 ,  TTF1_Q6 ,  MYB_Q5_01 ,  GCCATNTTG_YY1_Q6 ,  E2F1_Q4 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  SREBP1_01 ,  CACCCBINDINGFACTOR_Q6 ,  YY1_Q6 ,  CAGGTA_AREB6_01 ,  NFY_Q6_01 ,  ALPHACP1_01 ,  PXR_Q2 ,  EVI1_02 ,  EGR_Q6 ,  ZID_01 ,  CDPCR1_01 ,  GGGCGGR_SP1_Q6 ,  STAT5A_03 ,  GGCNRNWCTTYS_UNKNOWN ,  CTTTAAR_UNKNOWN ,  NF1_Q6_01 ,  TGTTTGY_HNF3_Q6 ,  SOX5_01 ,  MYB_Q6 ,  TTGTTT_FOXO4_01 ,  YY1_02 ,  CTGYNNCTYTAA_UNKNOWN ,  PAX_Q6 ,  WCAANNNYCAG_UNKNOWN ,  EGR1_01 ,  CAGCTG_AP4_Q5 ,  ER_Q6 ,  MYB_Q3

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Cytogenetic Map:

22q12.2

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