Correlation Engine 2.0
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QuickView for UBA1 (gene)

Gene Symbol:
UBA1 Homo sapiens Homo sapiens
Full name:
ubiquitin like modifier activating enzyme 1
A1S9, A1S9T, A1ST, AMCX1, CFAP124, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, ubiquitin-like modifier-activating enzyme 1, A1S9T and BN75 temperature sensitivity complementing, POC20 centriolar protein homolog, UBA1, ubiquitin-activating enzyme E1 homolog A, testicular secretory protein Li 63
Genomic Location:
Chr X: 46935204-46959471
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that e...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr X

GO Molecular Function

nucleic acid binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ubiquitin-like modifier activating enzyme activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ligase activity | ubiquitin activating enzyme activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding | RNA binding

GO Biological Process

cellular process | response to stimulus | response to stress | protein modification process | macromolecule modification | nitrogen compound metabolic process | cellular response to DNA damage stimulus | cellular response to stress | protein modification by small protein conjugation | protein metabolic process | protein ubiquitination | metabolic process | ubiquitin activating enzyme activity | organic substance metabolic process | protein modification by small protein conjugation or removal | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

rough endoplasmic reticulum membrane | chromosome | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | intracellular organelle | endoplasmic reticulum | cell-cell junction | endosome membrane | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | chromatin | vacuole | vesicle | extracellular exosome | mitochondrion | lytic vacuole | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | heterochromatin | nucleus | organelle | lysosome | extracellular space | membrane-enclosed lumen | desmosome | rough endoplasmic reticulum | cytosol | intracellular vesicle | intracellular | cell junction | lysosomal membrane | membrane | vacuolar membrane