QuickView for UBASH3B;jsessionid=881B5227603CACCA4FDF0D8C4AA8CA76 (gene)

Gene Symbol:

UBASH3B Homo sapiens

Full name:

ubiquitin associated and SH3 domain containing B

Synonyms:

STS-1, STS1, TULA-2, TULA2, p70, ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein Sts-1, SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate, T-cell ubiquitin ligand 2, cbl-interacting protein p70, nm23-phosphorylated unknown substrate, suppressor of T-cell receptor signaling 1, tyrosine-protein phosphatase STS1/TULA2

Genomic Location:

Chr 11: 122031640-122190391

Description:

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  HOXA4_Q2 ,  NGFIC_01 ,  EGR2_01 ,  PAX2_01 ,  CAGGTG_E12_Q6 ,  ACCAAAG_MIR9 ,  GACAATC_MIR219 ,  CTCTGGA_MIR520A_MIR525 ,  GTGGGTGK_UNKNOWN ,  EGR1_01 ,  AAACCAC_MIR140 ,  EGR3_01

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Cytogenetic Map:

11q24.1

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