QuickView for USH1F (gene)

Gene Symbol:

PCDH15 Homo sapiens

Full name:

protocadherin related 15

Synonyms:

CDHR15, DFNB23, USH1F, protocadherin-15, cadherin-related family member 15

Genomic Location:

Chr 10: 55250866-56231057

Description:

This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing res...

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This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  GCANCTGNY_MYOD_Q6 ,  CAGGTG_E12_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-376c

Cytogenetic Map:

10q21.1

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