QuickView for USO1;jsessionid=65EA5A6B48C3B93F32E3100D6A0C7125 (gene)

Gene Symbol:

USO1 Homo sapiens

Full name:

USO1 vesicle transport factor

Synonyms:

P115, TAP, VDP, general vesicular transport factor p115, USO1 vesicle docking protein homolog, transcytosis associated protein, vesicle docking protein p115

Genomic Location:

Chr 4: 76868853-76954390

Description:

The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat...

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The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYOD_Q6_01 ,  PBX1_02 ,  XBP1_01 ,  E2A_Q2 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  AREB6_01 ,  NRF1_Q6 ,  AHRARNT_01 ,  TTGTTT_FOXO4_01 ,  STAT5A_04 ,  GTGTCAA_MIR514 ,  CTTTGT_LEF1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  CAGCTG_AP4_Q5 ,  AACTTT_UNKNOWN ,  AP4_Q5 ,  CTAGGAA_MIR384 ,  HTF_01

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Cytogenetic Map:

4q21.1

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