QuickView for USP33 (gene)

Gene Symbol:

USP33 Homo sapiens

Full name:

ubiquitin specific peptidase 33

Synonyms:

VDU1, ubiquitin carboxyl-terminal hydrolase 33, VHL-interacting deubiquitinating enzyme 1, deubiquitinating enzyme 33, pVHL-interacting deubiquitinating enzyme 1, ubiquitin thioesterase 33, ubiquitin thiolesterase 33, ubiquitin-specific-processing protease 33

Genomic Location:

Chr 1: 77934260-77998125

Description:

This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms.

This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAC_MIR19A_MIR19B ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  TTTGTAG_MIR520D ,  TTGCACT_MIR130A_MIR301_MIR130B ,  GGGCATT_MIR365 ,  CTTTGTA_MIR524 ,  ACATTCC_MIR1_MIR206 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  ATGTTAA_MIR302C ,  ACTGCAG_MIR173P ,  AACATTC_MIR4093P

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-365 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-543 ,  Predicted Gene Targets for miR-378

Cytogenetic Map:

1p31.1

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