QuickView for USP36;jsessionid=5ACC29D3440EDE9A7D5758496D8936AC (gene)

Gene Symbol:

USP36 Homo sapiens

Full name:

ubiquitin specific peptidase 36

Synonyms:

DUB1, ubiquitin carboxyl-terminal hydrolase 36, deubiquitinating enzyme 36, ubiquitin specific protease 36, ubiquitin thioesterase 36, ubiquitin-specific-processing protease 36

Genomic Location:

Chr 17: 74304560-74348564

Description:

This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in mo...

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This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CACGTG_MYC_Q2 ,  CREB_Q3 ,  MYCMAX_02 ,  CREB_02 ,  CTTTAAR_UNKNOWN

Cytogenetic Map:

17q25.3

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