QuickView for VABP (gene)

Gene Symbol:

KCNIP1 Homo sapiens

Full name:

potassium voltage-gated channel interacting protein 1

Synonyms:

KCHIP1, VABP, Kv channel-interacting protein 1, A-type potassium channel modulatory protein 1, Kv channel interacting protein 1, potassium channel interacting protein 1, vesicle APC-binding protein

Genomic Location:

Chr 5: 169713459-170096214

Description:

This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating...

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This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  HSF_Q6 ,  PAX5_01 ,  CTGCAGY_UNKNOWN ,  AACTTT_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-150

Cytogenetic Map:

5q35.1

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