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QuickView for VARS;jsessionid=5CE19C31F6B7F7A2084DE12036F8C591 (gene)


Gene Symbol:
VARS Homo sapiens Homo sapiens
Full name:
valyl-tRNA synthetase
Synonyms:
G7A, NDMSCA, VARS1, VARS2, valine--tRNA ligase, protein G7a, valRS, valine tRNA ligase 1, cytoplasmic, valyl-tRNA synthetase 2
Genomic Location:
Chr 6: 31853274-31871691
Description:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Danio rerio Schizosaccharomyces pombe Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6
6p21.33





GO Molecular Function

ribonucleotide binding | carboxylic ester hydrolase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | aminoacyl-tRNA ligase activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | aminoacyl-tRNA editing activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | valine-tRNA ligase activity | ligase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | tRNA aminoacylation | cellular process | aminoacyl-tRNA metabolism involved in translational fidelity | cellular amino acid metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | peptide biosynthetic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | small molecule metabolic process | cellular amide metabolic process | tRNA aminoacylation for protein translation | translation | biosynthetic process | aminoacyl-tRNA editing activity | peptide metabolic process | carboxylic acid metabolic process | tRNA metabolic process | protein metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | amide biosynthetic process | organic acid metabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of translational fidelity | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | valyl-tRNA aminoacylation | macromolecule metabolic process

GO Cellular Component

cell | cytoplasm | cytosol | intracellular