QuickView for VDAC3 (gene)

Gene Symbol:

VDAC3 Homo sapiens

Full name:

voltage dependent anion channel 3

Synonyms:

HD-VDAC3, VDAC-3, voltage-dependent anion-selective channel protein 3, outer mitochondrial membrane protein porin 3

Genomic Location:

Chr 8: 42368547-42382572

Description:

This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation ...

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This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TMTCGCGANR_UNKNOWN ,  AGTCTAG_MIR151

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-151

Cytogenetic Map:

8p11.21

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