QuickView for WARS;jsessionid=AF95D61434E6EE47003B50410C51947B (gene)
- Gene Symbol:
- WARS
Homo sapiens - Full name:
- tryptophanyl-tRNA synthetase
- Synonyms:
- GAMMA-2, HMN9, IFI53, IFP53, tryptophan--tRNA ligase, cytoplasmic, hWRS, interferon-induced protein 53, trpRS, tryptophan tRNA ligase 1, cytoplasmic
- Genomic Location:
- Chr 14: 99869878-99912433
- Description:
-
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
14q32.2
GO Molecular Function
kinase binding | kinase regulator activity | protein kinase binding | enzyme binding | ribonucleotide binding | tryptophan-tRNA ligase activity | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | molecular function regulator | catalytic activity | aminoacyl-tRNA ligase activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | kinase inhibitor activity | protein dimerization activity | ligase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
RNA metabolic process | negative regulation of phosphorylation | positive regulation of cellular component organization | negative regulation of cellular process | negative regulation of kinase activity | tRNA aminoacylation | tryptophanyl-tRNA aminoacylation | negative regulation of protein phosphorylation | blood vessel morphogenesis | cellular process | kinase regulator activity | negative regulation of cellular metabolic process | cellular amino acid metabolic process | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of vasculature development | enzyme inhibitor activity | vasculature development | peptide biosynthetic process | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | cardiovascular system development | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | molecular function regulator | blood vessel development | system development | nitrogen compound metabolic process | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of protein complex assembly | cellular amide metabolic process | tRNA aminoacylation for protein translation | translation | biosynthetic process | regulation of cellular protein metabolic process | angiogenesis | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | peptide metabolic process | carboxylic acid metabolic process | tRNA metabolic process | protein metabolic process | kinase inhibitor activity | regulation of kinase activity | anatomical structure development | metabolic process | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of cellular protein metabolic process | gene expression | amide biosynthetic process | regulation of phosphate metabolic process | regulation of protein ADP-ribosylation | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | negative regulation of molecular function | organic acid metabolic process | cellular protein metabolic process | enzyme regulator activity | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | tube development | negative regulation of cell proliferation | ncRNA metabolic process | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | circulatory system development | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cytosol | intracellular
