QuickView for WDPCP;jsessionid=A4597E56A55F74B7E2AD8F5907045575 (gene)

Gene Symbol:

WDPCP Homo sapiens

Full name:

WD repeat containing planar cell polarity effector

Synonyms:

BBS15, C2orf86, CHDTHP, FRITZ, FRTZ, WD repeat-containing and planar cell polarity effector protein fritz homolog, Bardet-Biedl syndrome 15 protein, WD repeat-containing protein C2orf86

Genomic Location:

Chr 2: 63202022-63669355

Description:

This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternat...

View Full Description

This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PAX4_04 ,  MZF1_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  AREB6_02 ,  HOXA4_Q2 ,  AREB6_04 ,  CDP_01 ,  GGGNRMNNYCAT_UNKNOWN ,  CDPCR3HD_01 ,  PAX4_02 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  AP4_Q6 ,  NKX62_Q2 ,  NF1_Q6 ,  CDPCR1_01 ,  OCT1_03 ,  CTTTAAR_UNKNOWN ,  PAX6_01 ,  TGCCAAR_NF1_Q6 ,  NF1_Q6_01 ,  NCX_01 ,  CHX10_01 ,  TAATTA_CHX10_01 ,  AP2REP_01 ,  CART1_01 ,  TEF_Q6 ,  PAX5_01 ,  TGATTTRY_GFI1_01 ,  ICSBP_Q6 ,  GRE_C ,  CAGCTG_AP4_Q5 ,  PPAR_DR1_Q2 ,  ACCTGTTG_UNKNOWN

View More

View Less

Cytogenetic Map:

2p15

search → result