QuickView for WGEF (gene)
- Gene Symbol:
- ARHGEF19
Homo sapiens - Full name:
- Rho guanine nucleotide exchange factor 19
- Synonyms:
- WGEF, rho guanine nucleotide exchange factor 19, Rho guanine nucleotide exchange factor (GEF) 19, ephexin-2, weakly similar to Rho GEF
- Genomic Location:
- Chr 1: 16397186-16411691
- Description:
-
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1p36.13
GO Molecular Function
Rho guanyl-nucleotide exchange factor activity | guanyl-nucleotide exchange factor activity | enzyme activator activity | GTPase binding | Rho GTPase binding | GTPase activator activity | enzyme binding | GTPase regulator activity | Ras GTPase binding | molecular function regulator | protein binding | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | enzyme regulator activity
GO Biological Process
Rho guanyl-nucleotide exchange factor activity | guanyl-nucleotide exchange factor activity | enzyme activator activity | positive regulation of apoptotic process | regulation of programmed cell death | regulation of organelle organization | positive regulation of GTPase activity | cellular process | GTPase activator activity | positive regulation of catalytic activity | regulation of cellular process | regulation of apoptotic process | regulation of establishment of planar polarity | response to stimulus | GTPase regulator activity | response to stress | G-protein coupled receptor signaling pathway | Wnt signaling pathway, planar cell polarity pathway | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of signal transduction | Wnt signaling pathway | regulation of actin cytoskeleton organization | regulation of catalytic activity | wound healing | regulation of small GTPase mediated signal transduction | positive regulation of hydrolase activity | non-canonical Wnt signaling pathway | regulation of Rho protein signal transduction | regulation of GTPase activity | cell communication | positive regulation of molecular function | response to wounding | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | cell surface receptor signaling pathway | Ras guanyl-nucleotide exchange factor activity | positive regulation of cell death | positive regulation of programmed cell death | regulation of cell communication | signaling | enzyme regulator activity | regulation of Ras protein signal transduction | regulation of developmental process | regulation of actin filament-based process | regulation of cell death | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction | regulation of signaling
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
