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QuickView for WICH (gene)


Gene Symbol:
WIPF2 Homo sapiens Homo sapiens
Full name:
WAS/WASL interacting protein family member 2
Synonyms:
WICH, WIRE, WAS/WASL-interacting protein family member 2, WASP-binding protein, WASP-interacting protein-related protein, WIP- and CR16-homologous protein, WIP-related protein
Genomic Location:
Chr 17: 35629100-35691965
Description:
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery.
Orthologs:
Mus musculus Rattus norvegicus Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q21.2





GO Molecular Function

actin binding | actin filament binding | protein-containing complex binding | cytoskeletal protein binding | protein binding

GO Biological Process

positive regulation of immune response | regulation of supramolecular fiber organization | actin filament-based process | positive regulation of cellular component organization | immune response-regulating signaling pathway | actin cytoskeleton organization | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | regulation of organelle organization | regulation of actin polymerization or depolymerization | cellular process | positive regulation of actin filament polymerization | Fc-gamma receptor signaling pathway involved in phagocytosis | localization | actin filament-based movement | regulation of immune response | regulation of cellular process | regulation of protein complex assembly | cortical actin cytoskeleton organization | cellular component organization | regulation of actin filament length | response to stimulus | actin cortical patch assembly | positive regulation of immune system process | cellular localization | immune response-activating signal transduction | regulation of cellular component size | cellular component assembly | positive regulation of actin nucleation | positive regulation of organelle organization | regulation of actin cytoskeleton organization | regulation of actin filament organization | Fc-gamma receptor signaling pathway | positive regulation of protein complex assembly | vesicle-mediated transport | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | cell communication | regulation of actin filament polymerization | positive regulation of cytoskeleton organization | activation of immune response | import into cell | cell surface receptor signaling pathway | positive regulation of supramolecular fiber organization | endocytosis | regulation of actin nucleation | positive regulation of cellular component biogenesis | cytoskeleton organization | actin cortical patch localization | signaling | organelle organization | Fc receptor signaling pathway | cortical cytoskeleton organization | actin cortical patch organization | Fc receptor mediated stimulatory signaling pathway | positive regulation of protein polymerization | regulation of actin filament-based process | immune system process | phagocytosis | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction

GO Cellular Component

supramolecular fiber | intracellular membrane-bounded organelle | actin cortical patch | cell | nuclear lumen | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | nucleoplasm | plasma membrane | endocytic patch | cytoplasmic region | cortical actin cytoskeleton | cell cortex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | actin filament | cytoskeleton | intracellular | membrane | supramolecular complex