QuickView for WIPI1 (gene)

Gene Symbol:

WIPI1 Homo sapiens

Full name:

WD repeat domain, phosphoinositide interacting 1

Synonyms:

ATG18, ATG18A, WIPI49, WD repeat domain phosphoinositide-interacting protein 1, WIPI-1 alpha, atg18 protein homolog

Genomic Location:

Chr 17: 63929017-63965248

Description:

This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-...

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This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  GCANCTGNY_MYOD_Q6 ,  MYB_Q5_01 ,  CTAWWWATA_RSRFC4_Q2 ,  WTGAAAT_UNKNOWN ,  TATAAA_TATA_01 ,  HNF4_Q6 ,  MYCMAX_01 ,  CDPCR3_01 ,  GGGCGGR_SP1_Q6 ,  MGGAAGTG_GABP_B ,  NKX25_02 ,  USF_Q6_01 ,  TAATTA_CHX10_01 ,  WGGAATGY_TEF1_Q6 ,  AFP1_Q6 ,  WWTAAGGC_UNKNOWN ,  TEF_Q6 ,  CTTTGT_LEF1_Q2 ,  TBP_01 ,  MMEF2_Q6 ,  TGACATY_UNKNOWN ,  MYB_Q3

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Cytogenetic Map:

17q24.2

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