QuickView for WNT10B (gene)

Gene Symbol:

WNT10B Homo sapiens

Full name:

Wnt family member 10B

Synonyms:

SHFM6, STHAG8, WNT-12, protein Wnt-10b, WNT-10B protein, wingless-type MMTV integration site family, member 10B

Genomic Location:

Chr 12: 47645390-47651810

Description:

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and ...

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CEBPA_01 ,  ZIC1_01 ,  AREB6_02 ,  SMAD3_Q6 ,  CEBP_Q2_01 ,  NFKAPPAB_01 ,  ZIC3_01 ,  CTTTGA_LEF1_Q2 ,  RYCACNNRNNRNCAG_UNKNOWN ,  NFKAPPAB65_01 ,  CEBPDELTA_Q6 ,  RGAANNTTC_HSF1_01 ,  CEBPB_01 ,  CAGGTG_E12_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  E47_02 ,  GCM_Q2 ,  CEBP_Q3 ,  CEBP_C ,  MYOGENIN_Q6 ,  CP2_02 ,  CREL_01 ,  CAGCTG_AP4_Q5 ,  AP4_Q5 ,  LBP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-370

Cytogenetic Map:

12q13.12

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