QuickView for ZBU1 (gene)
- Gene Symbol:
- HLTF
Homo sapiens - Full name:
- helicase like transcription factor
- Synonyms:
- HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1, helicase-like transcription factor, DNA-binding protein/plasminogen activator inhibitor-1 regulator, RING finger protein 80, RING-type E3 ubiquitin transferase HLTF, SNF2-like 3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, sucrose nonfermenting protein 2-like 3, sucrose nonfermenting-like 3
- Genomic Location:
- Chr 3: 150230594-150287031
- Description:
-
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been foun...
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
3q24
| Transcripts Names |
|---|
| NM_003071 |
| NM_139048 |
| NM_001318934 |
| XM_017007079 |
| XM_017007078 |
| XM_011513092 |
| XM_011513091 |
| NM_001318935 |
| XM_011513093 |
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | catalytic activity | ATP binding | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | ubiquitin protein ligase activity | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | purine ribonucleoside triphosphate binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | ubiquitin protein ligase binding | ubiquitin-protein transferase activity | hydrolase activity, acting on acid anhydrides | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transferase activity | transition metal ion binding | ubiquitin-like protein ligase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of transcription by RNA polymerase II | ubiquitin protein ligase activity | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein metabolic process | DNA-binding transcription factor activity | protein ubiquitination | metabolic process | ubiquitin-protein transferase activity | regulation of RNA biosynthetic process | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | protein modification by small protein conjugation or removal | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | organelle organization | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | membrane
