QuickView for ZCRB1;jsessionid=1B1ED7053E85EBCC8A0241178E95F09A (gene)

Gene Symbol:

ZCRB1 Homo sapiens

Full name:

zinc finger CCHC-type and RNA binding motif containing 1

Synonyms:

MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19, zinc finger CCHC-type and RNA-binding motif-containing protein 1, U11/U12 small nuclear ribonucleoprotein 31 kDa protein, U11/U12 snRNP 31 kDa protein, U11/U12 snRNP 31K, U11/U12-31K, zinc finger CCHC-type and RNA binding motif 1

Genomic Location:

Chr 12: 40992155-41006199

Description:

Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition mot...

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Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YRTCANNRCGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  CETS1P54_01 ,  ELK1_01 ,  SCGGAAGY_ELK1_02 ,  WCAANNNYCAG_UNKNOWN ,  ELK1_02 ,  CREB_Q2_01

Cytogenetic Map:

12q12

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