QuickView for ZFYVE26 (gene)

Gene Symbol:

ZFYVE26 Homo sapiens

Full name:

zinc finger FYVE-type containing 26

Synonyms:

FYVE-CENT, SPG15, zinc finger FYVE domain-containing protein 26, FYVE domain-containing centrosomal protein, spastizin, zinc finger, FYVE domain containing 26

Genomic Location:

Chr 14: 67282992-67353055

Description:

This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.

This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGCCAT_MIR183 ,  TTTGCAC_MIR19A_MIR19B ,  TGANTCA_AP1_C ,  TCANNTGAY_SREBP1_01 ,  ARNT_01 ,  CACGTG_MYC_Q2 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  MAX_01 ,  AACTGGA_MIR145 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  ARNT_02 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  AR_Q6 ,  SREBP1_01 ,  CAGGTG_E12_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  USF_01 ,  TTGTTT_FOXO4_01 ,  AAGCACT_MIR520F ,  CAGCTG_AP4_Q5 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  P300_01 ,  USF_02 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-29

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Cytogenetic Map:

14q24.1

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