QuickView for ZIC1 (gene)

Gene Symbol:

ZIC1 Homo sapiens

Full name:

Zic family member 1

Synonyms:

CRS6, ZIC, ZNF201, zinc finger protein ZIC 1, Zic family member 1 (odd-paired homolog, Drosophila), Zinc finger protein of the cerebellum 1, zinc finger protein 201

Genomic Location:

Chr 3: 148609871-148617196

Description:

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome...

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This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PBX1_02 ,  OCT1_07 ,  FXR_Q3 ,  MCAATNNNNNGCG_UNKNOWN ,  GAGCCTG_MIR484 ,  TTTGCAG_MIR518A2 ,  GATA1_03 ,  GATA1_01 ,  OCT1_04 ,  NFAT_Q6 ,  HOXA4_Q2 ,  GATA_C ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  NKX3A_01 ,  CTTTGCA_MIR527 ,  GAGACTG_MIR452 ,  CIZ_01 ,  EVI1_04 ,  YATTNATC_UNKNOWN ,  IPF1_Q4 ,  HP1SITEFACTOR_Q6 ,  ATGTACA_MIR493 ,  ARNT_02 ,  FAC1_01 ,  CTTTGA_LEF1_Q2 ,  TTF1_Q6 ,  GTGCAAA_MIR507 ,  PBX1_01 ,  PAX3_01 ,  GATA1_04 ,  TCF4_Q5 ,  COMP1_01 ,  CTTTGTA_MIR524 ,  WTGAAAT_UNKNOWN ,  OSF2_Q6 ,  CEBPB_01 ,  SOX9_B1 ,  TAATGTG_MIR323 ,  TGCAAAC_MIR452 ,  PAX4_02 ,  CAGGTA_AREB6_01 ,  CATGTAA_MIR496 ,  TST1_01 ,  NKX62_Q2 ,  ZID_01 ,  ATGCTGC_MIR103_MIR107 ,  CDPCR3_01 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  TAATAAT_MIR126 ,  AP2_Q3 ,  POU1F1_Q6 ,  TGTTTGY_HNF3_Q6 ,  NRF2_Q4 ,  AP1_Q4 ,  PTF1BETA_Q6 ,  GFI1_01 ,  HMGIY_Q6 ,  AATGTGA_MIR23A_MIR23B ,  OCT1_02 ,  CHX10_01 ,  TAATTA_CHX10_01 ,  CCTGCTG_MIR214 ,  TTGTTT_FOXO4_01 ,  WGGAATGY_TEF1_Q6 ,  CEBP_C ,  AAAYRNCTG_UNKNOWN ,  AFP1_Q6 ,  GATA4_Q3 ,  MSX1_01 ,  RTTTNNNYTGGM_UNKNOWN ,  GTGTCAA_MIR514 ,  GATA1_05 ,  GGTAACC_MIR4095P ,  TGATTTRY_GFI1_01 ,  AP1_Q2 ,  RYAAAKNNNNNNTTGW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  ER_Q6_01 ,  P300_01 ,  GCTNWTTGK_UNKNOWN ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  HNF6_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-487b ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-409-5p ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

3q24

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