QuickView for Zc3hc1 (gene)
- Gene Symbol:
- ZC3HC1
Homo sapiens - Full name:
- zinc finger C3HC-type containing 1
- Synonyms:
- HSPC216, NIPA, nuclear-interacting partner of ALK, hematopoietic stem/progenitor cell protein 216, nuclear interacting partner of anaplastic lymphoma kinase (ALK)
- Genomic Location:
- Chr 7: 129445362-129478469
- Description:
-
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degra...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
7q32.2
GO Molecular Function
kinase binding | cation binding | protein kinase binding | enzyme binding | ion binding | protein binding | zinc ion binding | transition metal ion binding | metal ion binding
GO Biological Process
regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of programmed cell death | negative regulation of cellular process | cellular process | negative regulation of signaling | negative regulation of apoptotic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway | cell cycle | protein modification by small protein conjugation | negative regulation of extrinsic apoptotic signaling pathway | cell division | regulation of apoptotic signaling pathway | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | protein metabolic process | protein ubiquitination | metabolic process | negative regulation of programmed cell death | organic substance metabolic process | protein modification by small protein conjugation or removal | regulation of cell communication | negative regulation of signal transduction | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | intracellular organelle | endomembrane system | nuclear envelope | membrane-bounded organelle | nucleus | organelle | intracellular | membrane
