QuickView for Zip7 (gene)

Gene Symbol:

SLC39A7 Homo sapiens

Full name:

solute carrier family 39 member 7

Synonyms:

D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7, zinc transporter SLC39A7, HLA class II region expressed gene KE4, Ke4 gene, mouse, human homolog of, histidine-rich membrane protein Ke4, really interesting new gene 5 protein, solute carrier family 39 (zinc transporter), member 7, zrt-, Irt-like protein 7

Genomic Location:

Chr 6: 33276581-33280192

Description:

The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicin...

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The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  RTAAACA_FREAC2_01 ,  CACGTG_MYC_Q2 ,  AP2GAMMA_01 ,  AP2ALPHA_01 ,  GCCATNTTG_YY1_Q6 ,  GGGAGGRR_MAZ_Q6 ,  DBP_Q6 ,  YY1_Q6 ,  FOXO3_01 ,  GGGCGGR_SP1_Q6 ,  GGCNKCCATNK_UNKNOWN ,  USF_C ,  HIF1_Q5 ,  IRF_Q6 ,  TGTTTGY_HNF3_Q6 ,  NRF1_Q6 ,  ELK1_01 ,  TTGTTT_FOXO4_01 ,  SCGGAAGY_ELK1_02 ,  ACAWNRNSRCGG_UNKNOWN ,  RCGCANGCGY_NRF1_Q6 ,  NFKB_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125

Cytogenetic Map:

6p21.32

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