QuickView for Zuo1;jsessionid=2BBF485A40849C9ABC4DC662B1860C4B;jsessionid=2B06510FDF0B850A877874C3E72FD82F;jsessionid=B38D70C451D6B3ECB2A3DE468E8238AB;jsessionid=0E7EED0B8BC9494EFECF9479DC69449F;jsessionid=CC929E96EC63EEA50D77F91366F257E5;jsessionid=1096ABB7F927A8C1ED39CFCB6043D6FD;jsessionid=2B2ABF11F5DF41EA49495702E5626E00;jsessionid=C006EA7ED803863558D9E7235B931B18 (gene)
- Gene Symbol:
- DNAJC2
Homo sapiens - Full name:
- DnaJ heat shock protein family (Hsp40) member C2
- Synonyms:
- MPHOSPH11, MPP11, ZRF1, ZUO1, dnaJ homolog subfamily C member 2, DnaJ (Hsp40) homolog, subfamily C, member 2, M-phase phosphoprotein 11, zuotin-related factor 1
- Genomic Location:
- Chr 7: 102740157-102772556
- Description:
-
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
7q22.1
| Transcripts Names |
|---|
| NM_014377 |
| NM_001129887 |
| XM_011516029 |
| XM_005250269 |
| XM_017011968 |
| XM_011516030 |
| XM_011516028 |
GO Molecular Function
enzyme activator activity | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | molecular function regulator | chromatin binding | Hsp70 protein binding | modification-dependent protein binding | DNA binding | organic cyclic compound binding | protein binding | ATPase activator activity | DNA-binding transcription factor activity | ubiquitin modification-dependent histone binding | histone binding | enzyme regulator activity | ATPase regulator activity | heat shock protein binding | heterocyclic compound binding | ubiquitin-dependent protein binding | RNA binding
GO Biological Process
RNA metabolic process | positive regulation of ATPase activity | positive regulation of macromolecule biosynthetic process | 'de novo' cotranslational protein folding | enzyme activator activity | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of DNA metabolic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of DNA biosynthetic process | chromatin organization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of cellular response to heat | regulation of ATPase activity | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | molecular function regulator | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | nitrogen compound metabolic process | regulation of catalytic activity | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | positive regulation of hydrolase activity | biosynthetic process | 'de novo' protein folding | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | positive regulation of molecular function | ATPase activator activity | DNA-binding transcription factor activity | DNA metabolic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | protein folding | negative regulation of biosynthetic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | enzyme regulator activity | cellular macromolecule biosynthetic process | organelle organization | regulation of DNA biosynthetic process | positive regulation of transcription, DNA-templated | ATPase regulator activity | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | DNA replication | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | nuclear lumen | cytoplasm | intracellular organelle | endomembrane system | nucleoplasm | nuclear envelope | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | membrane
