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QuickView for agrin (gene)


Gene Symbol:
Agrn Rattus norvegicus Rattus norvegicus
Full name:
agrin
Synonyms:
AGR, agrin
Genomic Location:
Chr 5: 172999420-173020764
Description:
may play a role in synapse development and regeneration
Orthologs:
Homo sapiens Mus musculus C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

transforming growth factor beta binding | cytokine binding | proteoglycan binding | BMP binding | cation binding | carboxylic acid binding | acetylcholine receptor regulator activity | enzyme inhibitor activity | sialic acid binding | carbohydrate derivative binding | growth factor binding | molecular function regulator | ion channel binding | extracellular matrix binding | anion binding | dystroglycan binding | chondroitin sulfate binding | ion binding | heparan sulfate proteoglycan binding | laminin binding | protein binding | receptor regulator activity | glycosaminoglycan binding | calcium ion binding | enzyme regulator activity | ATPase regulator activity | organic acid binding | metal ion binding | ATPase inhibitor activity | small molecule binding

GO Biological Process

regulation of muscle system process | positive regulation of macromolecule biosynthetic process | protein heterotetramerization | positive regulation of cellular component organization | regulation of cell morphogenesis | positive regulation of filopodium assembly | regulation of neurogenesis | regulation of sodium ion transmembrane transporter activity | regulation of synapse assembly | positive regulation of apoptotic process | regulation of cell development | regulation of localization | regulation of programmed cell death | regulation of sodium ion transport | positive regulation of peptidyl-tyrosine phosphorylation | response to hormone | negative regulation of potassium ion transport | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | response to drug | neurogenesis | positive regulation of phosphate metabolic process | regulation of organelle organization | generation of neurons | membrane organization | regulation of neuron death | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | negative regulation of sodium:potassium-exchanging ATPase activity | localization | acetylcholine receptor signaling pathway | regulation of sodium ion transmembrane transport | chemical synaptic transmission | synapse assembly | positive regulation of protein kinase activity | macromolecule localization | regulation of chemotaxis | endomembrane system organization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of binding | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | regulation of axon guidance | cellular component organization | positive regulation of protein binding | acetylcholine receptor regulator activity | response to stimulus | enzyme inhibitor activity | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | regulation of ATPase activity | regulation of blood circulation | receptor clustering | regulation of neurotransmitter receptor activity | negative regulation of transporter activity | cellular localization | positive regulation of neuromuscular junction development | negative regulation of transport | G-protein coupled receptor signaling pathway | positive regulation of RNA biosynthetic process | cellular component assembly | negative regulation of potassium ion transmembrane transport | regulation of cardiac muscle cell membrane potential | regulation of synapse structure or activity | cell-cell signaling | negative regulation of transmembrane transport | molecular function regulator | positive regulation of protein geranylgeranylation | regulation of nucleic acid-templated transcription | regulation of potassium ion transmembrane transport | regulation of membrane potential | response to nitrogen compound | cellular response to hormone stimulus | regulation of cell projection assembly | regulation of protein tyrosine kinase activity | system development | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | G-protein coupled acetylcholine receptor signaling pathway | regulation of axonogenesis | protein complex oligomerization | regulation of muscle contraction | regulation of catalytic activity | regulation of phosphorylation | negative regulation of sodium ion transmembrane transporter activity | plasma membrane organization | localization within membrane | cellular response to ammonium ion | regulation of neuron differentiation | regulation of gene expression | protein localization to membrane | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | neuromuscular junction development | response to ammonium ion | response to acetylcholine | regulation of synapse organization | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | regulation of cellular component movement | regulation of transcription by RNA polymerase II | synapse organization | positive regulation of hydrolase activity | negative regulation of ion transmembrane transport | regulation of cellular protein metabolic process | negative regulation of ion transport | positive regulation of neuron death | protein tetramerization | regulation of GTPase activity | regulation of heart contraction | regulation of potassium ion transmembrane transporter activity | cellular response to drug | regulation of striated muscle contraction | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | regulation of sodium:potassium-exchanging ATPase activity | regulation of cardiac muscle contraction | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | postsynaptic membrane organization | positive regulation of synapse assembly | regulation of filopodium assembly | regulation of microtubule-based process | regulation of potassium ion transport | positive regulation of molecular function | skeletal muscle acetylcholine-gated channel clustering | regulation of signaling receptor activity | receptor regulator activity | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | positive regulation of protein modification process | regulation of growth | response to organic substance | negative regulation of ATPase activity | regulation of kinase activity | positive regulation of neuron apoptotic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | cellular protein localization | positive regulation of synaptic growth at neuromuscular junction | positive regulation of cell death | positive regulation of cellular component biogenesis | negative regulation of ion transmembrane transporter activity | organic substance metabolic process | negative regulation of sodium ion transmembrane transport | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | negative regulation of potassium ion transmembrane transporter activity | regulation of ion transmembrane transport | positive regulation of binding | negative regulation of sodium ion export across plasma membrane | regulation of cell communication | negative regulation of molecular function | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | regulation of protein binding | regulation of developmental growth | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | enzyme regulator activity | protein heterooligomerization | cellular macromolecule localization | positive regulation of plasma membrane bounded cell projection assembly | regulation of nervous system development | regulation of developmental process | regulation of ion transport | developmental process | neurotransmitter receptor metabolic process | regulation of transport | positive regulation of transcription, DNA-templated | ATPase regulator activity | regulation of neuromuscular junction development | receptor metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | negative regulation of hydrolase activity | regulation of synaptic growth at neuromuscular junction | positive regulation of metabolic process | negative regulation of sodium ion transport | regulation of cell projection organization | cellular metabolic process | cellular response to organic substance | regulation of cell death | ATPase inhibitor activity | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

synaptic cleft | integral component of membrane | sarcolemma | synapse | neuron projection | extracellular matrix | basement membrane | cell | distal axon | intrinsic component of membrane | cytoplasm | collagen-containing extracellular matrix | cell projection | plasma membrane | site of polarized growth | axonal growth cone | extracellular region | extracellular space | cell periphery | axon | growth cone | cytosol | cell surface | intracellular | cell junction | membrane