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Name: Antibodies, Antineutrophil Cytoplasmic
Description: Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for WEGENER GRANULOMATOSIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.
Cytoplasmic Antibodies, Anti-Neutrophil; Anti-Neutrophil Cytoplasmic Antibody; Cytoplasmic Antibodies, Antineutrophil; Antineutrophil Cytoplasmic Antibody; Cytoplasmic Antibody, Anti-Neutrophil; Antibody, Antineutrophil Cytoplasmic; Antineutrophil Cytoplasmic Antibodies; Anti-Neutrophil Cytoplasmic Antibodies; ANCA; Cytoplasmic Antibody, Antineutrophil.
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